Adrenaline 1:10,000 โ Post-ROSC Inotropic Support
NWAS NW0140 v15.27 โ Approved 05 Feb 2025
All NWAS Paramedics authorised following completion of training and competency assessment. โฅ12 years and adult only.
โถ Indications โ ALL THREE must be present
โฌSystolic BP <100 mmHg
โฌHR <100 bpm
โฌRadial pulse ABSENT
Note โ Radial pulse present & SBP <100
Consider 250mL NaCl 0.9% IV/IO first. Radial pulse must be absent before giving adrenaline.
โ Contraindications โ do not give if any present
ABSOLUTE CONTRAINDICATIONS
Core temperature <30ยฐC | SBP >100 mmHg | HR >100 bpm | Radial pulse present
โ Cautions
Temperature 30โ35ยฐC
Double the interval between doses (i.e. every 6โ10 minutes instead of 3โ5 minutes) โ per Resuscitation Council guidelines.
Non-cardioselective beta-blockers (e.g. propranolol)
Risk of severe hypertension.
Extravasation risk
Administer into a large vein or IO. If extravasation occurs: stop, gain new access, remove affected line, inform hospital, complete incident form.
โ Preparation โ 3-Way Tap Method
1. Use adrenaline pre-filled syringe 1mg in 10mL (1:10,000)
2. Attach a 3-way tap to the pre-filled syringe
3. Attach an empty 1mL or 2mL syringe to another port of the 3-way tap
4. Close the 3rd port on the 3-way tap
โ Do NOT attach the 3-way tap to the patient โ used for decanting only
5. Decant 50 micrograms (0.5mL) into the empty syringe, then remove from tap before administering
๐ Dosing
1
Initial Dose ยท โฅ12 yrs & adult
Adrenaline 1:10,000 โ 50 micrograms
0.5mL decanted via 3-way tap โ administer IV/IO bolus + 20mL NaCl 0.9% flush
โฌ
2+
Repeat Doses ยท Every 3โ5 min (6โ10 min if temp 30โ35ยฐC)
Adrenaline 1:10,000 โ 50โ100 micrograms
0.5โ1.0mL IV/IO bolus + 20mL NaCl 0.9% flush. No maximum dose limit.
โฌ
Stop when: SBP >100 mmHg achieved
Reassess BP, HR and radial pulse before each dose. Record each dose as an event on defib equipment using the "Event" button.
๐ Pre-Dose Checklist (before each dose)
โฌBP measured and SBP <100 mmHg confirmed
โฌHR <100 bpm confirmed
โฌRadial pulse absent confirmed
โฌCore temp โฅ30ยฐC confirmed (contraindicated if <30ยฐC)
โฌEach dose recorded as event on defib equipment